For first time, a cell built from scratch grows and divides(quantamagazine.org)
874 points by defrost 22 hours ago | 279 comments
tl;dr: Researchers led by Kate Adamala at the University of Minnesota assembled a synthetic cell from nonliving biological components that can grow, replicate its DNA, and divide—achieving cell division by using membrane-bending proteins instead of a cytoskeleton. The "spudcells" still require external supplies of ribosomes and nutrients and lack true natural selection (mutations must be introduced synthetically), so they aren't self-sustaining life, but the work represents the furthest progress yet toward building a living cell from scratch. The team is releasing methods via a new nonprofit, Biotic.
HN Discussion:
  • Explains the significance of ditching the cytoskeleton as a key breakthrough in the field
  • Notes skepticism from peers and criticism of Adamala's unusual publicity-seeking approach bypassing peer review
  • ~Questions how truly 'from scratch' the work is, given borrowed genes and chirality issues
  • Speculative sci-fi extrapolation imagining Biotic dominating future civilization
  • Requests expert clarification on technical implications of the approach