| The worthlessness of Vitamin D is mildly exaggerated(dynomight.net) | |
| 334 points by surprisetalk 20 hours ago | 245 comments | |
tl;dr: Vitamin D RCTs have refuted the magical correlations (no 30% mortality reduction), but the author argues skeptics overcorrected: trials consistently show hazard ratios slightly below 1 for cancer and all-cause mortality, and detecting modest-but-meaningful effects would require sample sizes far larger than any trial conducted. Combined with evolutionary evidence (ancestral levels ~115 nmol/L, pale skin evolving despite folate costs) and biology (vitamin D receptors throughout the body), supplementing if you have low-ish levels is probably worthwhile—even a HR of 0.96 would beat the cost of a daily pill. | |
HN Discussion:
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